FANCD2 antibody (AA 1401-1451)

Catalog No. ABIN7453818

This anti-FANCD2 antibody is a Rabbit Polyclonal antibody detecting FANCD2 in WB, IP and IHC (fp). Suitable for Human.

Quick Overview for FANCD2 antibody (AA 1401-1451) (ABIN7453818)

Target: FANCD2 (Fanconi Anemia, Complementation Group D2 (FANCD2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FANCD2 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Product Details anti-FANCD2 Antibody

Binding Specificity: AA 1401-1451

Purpose: Rabbit anti-FANCD2 Antibody, Affinity Purified

Predicted Reactivity: Monkey,Gorilla

Purification: Affinity Purified

Immunogen: between AA 1401 and 1451

Isotype: IgG

Application Details

Application Notes:

IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 5 - 15 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for FANCD2

Target: FANCD2 (Fanconi Anemia, Complementation Group D2 (FANCD2))

Alternative Name: FANCD2

Background: Background: FANCD2 (Fanconi anemia, complementation group D) is a protein involved in DNA repair. Defects in FANCD2 are the cause of Fanconi anemia, a heterogenous autosomal recessive disorder characterized by congenital malformations and a predisposition to cancer. The FANCD2 gene is one of 13 complementation groups that include FANCA, FANCB, FANCC, FANCD1/BRCA2, FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ/BRIP1, FANCL, FANCM, and FANCN/PALB2. The FANC members are not homologous proteins but are related by their assembly into a common nuclear complex.

Gene ID: 2177

NCBI Accession: NP_001018125

UniProt: Q9BXW9

Pathways: DNA Damage Repair