Paxillin antibody (AA 1-50)
Quick Overview for Paxillin antibody (AA 1-50) (ABIN7453855)
Target
See all Paxillin (PXN) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 1-50
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Purpose
- Rabbit anti-Paxillin Antibody, Affinity Purified
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Predicted Reactivity
- Orangutan
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Purification
- Affinity Purified
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Immunogen
- between AA 1 and 50
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Isotype
- IgG
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Application Notes
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IHC: 1:100 - 1:500. Epitope retrieval with Tris-EDTA pH 9.0 is recommended for FFPE tissue sections.
IP: 1 - 5 μg/mg lysate
WB: 1:5,000 - 1:20,000
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Restrictions
- For Research Use only
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Concentration
- 200 μg/mL
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Buffer
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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Expiry Date
- 12 months
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- Paxillin (PXN)
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Alternative Name
- Paxillin
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Background
- Background: Paxillin functions as a signal transduction adaptor protein that localizes to focal adhesions and is involved in cell-adhesion and motility. Paxillin is a substrate of several protein kinases such as Src, FAK, and JNK. Serine and threonine phosphorylation of Paxillin appears to dictate its specific cellular activities.
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Gene ID
- 5829
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NCBI Accession
- NP_001074324
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UniProt
- P49023
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Pathways
- MAPK Signaling, EGFR Signaling Pathway, Response to Growth Hormone Stimulus, Cell-Cell Junction Organization, Maintenance of Protein Location, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling
Target
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