CRTC3 antibody (AA 569-619)

Catalog No. ABIN7453868

The Rabbit Polyclonal anti-CRTC3 antibody has been validated for WB, IP and IHC (fp). It is suitable to detect CRTC3 in samples from Human.

Quick Overview for CRTC3 antibody (AA 569-619) (ABIN7453868)

Target: CRTC3 (CREB Regulated Transcription Coactivator 3 (CRTC3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CRTC3 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Product Details anti-CRTC3 Antibody

Binding Specificity: AA 569-619

Purpose: Rabbit anti-TORC3 Antibody, Affinity Purified

Predicted Reactivity: Mouse

Purification: Affinity Purified

Immunogen: between AA 569 and 619

Isotype: IgG

Application Details

Application Notes:

IHC: 1:100 - 1:500. Epitope retrieval with Tris-EDTA pH 9.0 is recommended for FFPE tissue sections.

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for CRTC3

Target: CRTC3 (CREB Regulated Transcription Coactivator 3 (CRTC3))

Alternative Name: TORC3

Background: Background: TORC3 (transducer of regulated cAMP response element-binding protein 3) is a transcriptional coactivator for CREB1 which activates transcription through cAMP response element (CRE) sites. TORC3 acts as a coactivator in the SIK/TORC signaling pathway. TORC3 has also been shown to be a coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR).

Gene ID: 64784

NCBI Accession: NP_073606

UniProt: Q6UUV7

Pathways: SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection