CDKL5 antibody (AA 350-400)

Catalog No. ABIN7453908

This Rabbit Polyclonal antibody specifically detects CDKL5 in WB, IP and IHC (fp). It exhibits reactivity toward Human.

Quick Overview for CDKL5 antibody (AA 350-400) (ABIN7453908)

Target: CDKL5 (Cyclin-Dependent Kinase-Like 5 (CDKL5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDKL5 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Product Details anti-CDKL5 Antibody

Binding Specificity: AA 350-400

Purpose: Rabbit anti-CDKL5 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: Between AA 350 and 400

Isotype: IgG

Application Details

Application Notes:

IHC: 1:2,000 - 1:10,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:1,000 - 1:5,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for CDKL5

Target: CDKL5 (Cyclin-Dependent Kinase-Like 5 (CDKL5))

Alternative Name: CDKL5

Background: Background: Cyclin-dependent kinase-like 5 (CDKL5) is a member of Ser/Thr protein kinase family and encodes a phosphorylated protein with protein kinase activity. Mutations in the CDKL5 gene have been associated with X-linked infantile spasm syndrome (ISSX), also known as X-linked West syndrome, and Rett syndrome (RTT) [taken from NCBI Entrez Gene (Gene ID: 6792)].

Gene ID: 6792

NCBI Accession: NP_003150

UniProt: O76039

Pathways: Regulation of Cell Size