PRMT1 antibody (AA 1-50)

Catalog No. ABIN7453933

The Rabbit Polyclonal anti-PRMT1 antibody has been validated for WB, IP and IHC (fp). It is suitable to detect PRMT1 in samples from Human and Mouse.

Quick Overview for PRMT1 antibody (AA 1-50) (ABIN7453933)

Target: PRMT1 (Protein Arginine Methyltransferase 1 (PRMT1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRMT1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Product Details anti-PRMT1 Antibody

Binding Specificity: AA 1-50

Purpose: Rabbit anti-PRMT1 Antibody, Affinity Purified

Predicted Reactivity: Rat

Purification: Affinity Purified

Immunogen: between AA 1 and 50

Isotype: IgG

Application Details

Application Notes:

IHC: 1:2,000 - 1:10,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for PRMT1

Target: PRMT1 (Protein Arginine Methyltransferase 1 (PRMT1))

Alternative Name: PRMT1

Background: Background: Protein arginine methylation is a form of post-translational modification that is catalyzed by protein arginine methyltransferases (PRMTs). Substrates of PRMT1 include RNA binding proteins, histones, and the DNA damage response proteins MRE11 and 53BP1. These interactions suggest a role for PRMT1 in the regulation of RNA metabolism, transcription and the DNA damage response.

Gene ID: 3276

NCBI Accession: NP_001527

UniProt: Q99873