Recombinant CD11b antibody (AA 17-334)

Catalog No. ABIN7453958

This anti-CD11b antibody is a Rabbit Monoclonal antibody detecting CD11b in IHC, WB, IP and ICC. Suitable for Human.

Quick Overview for Recombinant CD11b antibody (AA 17-334) (ABIN7453958)

Target: CD11b (ITGAM) (Integrin alpha M (ITGAM))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CD11b antibody is un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Clone: BLR107H

Product Details anti-CD11b Antibody

Binding Specificity: AA 17-334

Purpose: Rabbit anti-CD11b Recombinant Monoclonal Antibody [BLR107H]

Immunogen: residues 17-334 (ECD)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Borate Buffered Saline (BBS) pH 8.2 with 0.09 % Sodium Azide, BSA-Free

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for CD11b

Target: CD11b (ITGAM) (Integrin alpha M (ITGAM))

Alternative Name: CD11b

Background: Background: CD11b is the most commonly used name for Integrin alpha M (ITGAM). Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. ITGAM combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). ITGAM/ITGB2 is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. [taken from NCBI Entrez Gene (Gene ID: 3684)].

Gene ID: 3684

NCBI Accession: NP_001139280

UniProt: P11215

Pathways: Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation