ARID1B antibody (AA 1850-1900)

Catalog No. ABIN7454386

The Rabbit Polyclonal anti-ARID1B antibody has been validated for IP and IHC (fp). It is suitable to detect ARID1B in samples from Human.

Quick Overview for ARID1B antibody (AA 1850-1900) (ABIN7454386)

Target: ARID1B (AT Rich Interactive Domain 1B (SWI1-Like) (ARID1B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARID1B antibody is un-conjugated

Application: Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Product Details anti-ARID1B Antibody

Binding Specificity: AA 1850-1900

Purpose: Rabbit anti-ARID1B Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 1850 and 1900

Isotype: IgG

Application Details

Application Notes:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: Not recommended. Use rabbit anti-ARID1B antibody A301-046A.

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for ARID1B

Target: ARID1B (AT Rich Interactive Domain 1B (SWI1-Like) (ARID1B))

Alternative Name: ARID1B

Background: Background: The SWI/SNF-related, matrix-associated, actin-dependent regulators of chromatin (SMARC), also called BRG1-associated factors (BAFs), have been identified as components of the human SWI/SNF-like chromatin-remodeling protein complexes. SWI/SNF complexes possess ATPase and DNA helicase activity that promotes transcriptional activation of genes normally repressed by chromatin structure. ARID1B is a noncatalytic subunit that is a member of the ARID (AT-rich interactive domain-containing protein) family of DNA binding proteins. ARID1B is encoded by a gene independent from ARID1A and exhibits functionally distinct characteristics.

Gene ID: 57492

NCBI Accession: NP_059989

UniProt: Q8NFD5