TOR1AIP1 antibody (AA 275-325)

Catalog No. ABIN7454431

Product Details anti-TOR1AIP1 Antibody

Target: TOR1AIP1 (Torsin A Interacting Protein 1 (TOR1AIP1))

Binding Specificity: AA 275-325

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TOR1AIP1 antibody is un-conjugated

Application: Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Purpose: Rabbit anti-LAP1B Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 275 and 325

Isotype: IgG

Application Details

Application Notes:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 5 μg/mg lysate

WB: Not recommended. Use rabbit anti-LAP1B antibody A302-081A.

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for TOR1AIP1

Target: TOR1AIP1 (Torsin A Interacting Protein 1 (TOR1AIP1))

Alternative Name: LAP1B (TOR1AIP1 Products)

Synonyms: LAP1 antibody, LAP1B antibody, Lap1B antibody, Lap1b antibody, Lap1c antibody, torsin 1A interacting protein 1 antibody, torsin A interacting protein 1 antibody, TOR1AIP1 antibody, Tor1aip1 antibody

Background: Background: Lamina-associated polypeptide 1B (LAPB1) binds to A- and B-type lamins. It is a single-pass membrane protein that localizes to the inner membrane of the nucleus and may play a role in membrane attachment and the assembly of the nuclear lamina. LAPB1 is also called torsin-1A-interacting protein 1 (TOR1AIP1) due to its association with torsin, an ATPase of the AAA- (adenosine triphosphatases associated with diverse cellular activities) family of proteins.

Gene ID: 26092

NCBI Accession: NP_056417

UniProt: Q5JTV8

Pathways: SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection