SOD1 antibody (AA 104-154)

Catalog No. ABIN7454563

The Rabbit Polyclonal anti-SOD1 antibody has been validated for WB and IHC (fp). It is suitable to detect SOD1 in samples from Human.

Quick Overview for SOD1 antibody (AA 104-154) (ABIN7454563)

Target: SOD1 (Superoxide Dismutase 1, Soluble (SOD1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SOD1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Product Details anti-SOD1 Antibody

Binding Specificity: AA 104-154

Purpose: Rabbit anti-SOD1 Antibody, Affinity Purified

Predicted Reactivity: Mouse,Rat,Dog,Guinea pig_10141,Chimpanzee

Purification: Affinity Purified

Immunogen: Between AA 104 and 154

Isotype: IgG

Application Details

Application Notes:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: Not recommended

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for SOD1

Target: SOD1 (Superoxide Dismutase 1, Soluble (SOD1))

Alternative Name: SOD1

Background: Background: Superoxide dismutase 1 (SOD1) binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. SOD1 is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis [taken from NCBI Entrez Gene (Gene ID: 6647)].

Gene ID: 6647

NCBI Accession: NP_000445

UniProt: P00441

Pathways: Sensory Perception of Sound, Transition Metal Ion Homeostasis