Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

DNMT3A antibody (AA 125-175)

The Rabbit Polyclonal anti-DNMT3A antibody is suitable to detect DNMT3A in samples from Human and Mouse. It has been validated for WB and IHC (fp).
Catalog No. ABIN7454575
$538.15
Plus shipping costs $50.00
Shipping to: United States
Delivery in 3 to 5 Business Days

Quick Overview for DNMT3A antibody (AA 125-175) (ABIN7454575)

Target

See all DNMT3A Antibodies
DNMT3A (DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A))

Reactivity

  • 152
  • 64
  • 63
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human, Mouse

Host

  • 132
  • 21
Rabbit

Clonality

  • 111
  • 42
Polyclonal

Conjugate

  • 61
  • 11
  • 8
  • 8
  • 6
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This DNMT3A antibody is un-conjugated

Application

  • 101
  • 51
  • 44
  • 38
  • 26
  • 26
  • 18
  • 16
  • 11
  • 10
  • 9
  • 6
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
  • Binding Specificity

    • 16
    • 16
    • 13
    • 8
    • 8
    • 7
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 125-175

    Purpose

    Rabbit anti-DNMT3A Antibody, Affinity Purified

    Purification

    Affinity Purified

    Immunogen

    Between AA 125 and 175

    Isotype

    IgG
  • Application Notes

    IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

    IP: Not recommended

    WB: 1:2,000 - 1:10,000

    Restrictions

    For Research Use only
  • Concentration

    1000 μg/mL

    Buffer

    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    4 °C

    Expiry Date

    12 months
  • Target

    DNMT3A (DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A))

    Alternative Name

    DNMT3A

    Background

    Background: DNA cytosine methyltransferase 3A2 (DNMT3A) is required for genome-wide de novo methylation and is essential for the establishment of DNA methylation patterns during development. DNA methylation is coordinated with methylation of histones. DNMT3A modifies DNA in a non-processive manner and also methylates non-CpG sites. It may preferentially methylate DNA linker between 2 nucleosomal cores and is inhibited by histone H1. DNMT3A plays a role in paternal and maternal imprinting and is required for methylation of most imprinted loci in germ cells [taken from the Universal Protein Resource (UniProt) Q9Y6K1].

    Gene ID

    1788

    NCBI Accession

    NP_783328

    UniProt

    Q9Y6K1
You are here:
Chat with us!