Cortactin antibody (AA 450-500)

Catalog No. ABIN7454844

This Rabbit Polyclonal antibody specifically detects Cortactin in WB, IP and IHC (fp). It exhibits reactivity toward Human.

Quick Overview for Cortactin antibody (AA 450-500) (ABIN7454844)

Target: Cortactin (CTTN)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cortactin antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Product Details anti-Cortactin Antibody

Binding Specificity: AA 450-500

Purpose: Rabbit anti-Cortactin Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 450 and 500

Isotype: IgG

Application Details

Application Notes:

IHC: 1:200 - 1:1,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for Cortactin

Target: Cortactin (CTTN)

Alternative Name: Cortactin

Background: Background: Cortactin has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. The aberrant regulation of cortactin contributes to tumor cell invasion and metastasis [taken from NCBI Entrez Gene (GeneID: 2017)].

Gene ID: 2017

NCBI Accession: NP_005222

UniProt: Q14247

Pathways: MAPK Signaling