COMT antibody (AA 221-271)

Catalog No. ABIN7454936

This anti-COMT antibody is a Rabbit Polyclonal antibody detecting COMT in WB, IP and IHC (fp). Suitable for Human.

Quick Overview for COMT antibody (AA 221-271) (ABIN7454936)

Target: COMT (Catechol-O-Methyltransferase (COMT))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COMT antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Product Details anti-COMT Antibody

Binding Specificity: AA 221-271

Purpose: Rabbit anti-COMT Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: Between AA 221 and 271

Isotype: IgG

Application Details

Application Notes:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for COMT

Target: COMT (Catechol-O-Methyltransferase (COMT))

Alternative Name: COMT

Background: Background: Catechol O-mehtyltransferase (COMT) catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. Also shortens the biological half-lives of certain neuroactive drugs, like L-DOPA, alpha-methyl DOPA and isoproterenol [taken from the Universal Protein Resource (UniProt) P21964].

Gene ID: 1312

NCBI Accession: NP_000745

UniProt: P21964

Pathways: Steroid Hormone Biosynthesis, SARS-CoV-2 Protein Interactome