IL-2 antibody

Catalog No. ABIN7490458

The Rabbit Monoclonal anti-IL-2 antibody has been validated for ELISA and FACS. It is suitable to detect IL-2 in samples from Human.

Quick Overview for IL-2 antibody (ABIN7490458)

Target: IL-2 (IL2) (Interleukin 2 (IL2))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This IL-2 antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS)

Product Details anti-IL-2 Antibody

Characteristics: Rabbit IgG

Purification: Purified from cell culture supernatant by affinity chromatography

Isotype: IgG

Application Details

Application Notes: ELISA 1:5000-10000, Flow Cyt  1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Expiry Date: 12 months

Target Details for IL-2

Target: IL-2 (IL2) (Interleukin 2 (IL2))

Alternative Name: IL2

Background: IL-2, lymphokine, TCGF,
Description: This gene is a member of the interleukin 2 (IL2) cytokine subfamily which includes IL4, IL7, IL9, IL15, IL21, erythropoietin, and thrombopoietin. The protein encoded by this gene is a secreted cytokine produced by activated CD4 and CD8 T lymphocytes, that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine (IL2R) is a heterotrimeric protein complex whose gamma chain is also shared by IL4 and IL7. The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli.

UniProt: P60568

Pathways: JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation