Neuregulin 1 antibody
Quick Overview for Neuregulin 1 antibody (ABIN7490502)
Target
See all Neuregulin 1 (NRG1) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Characteristics
- Rabbit IgG
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Purification
- Purified from cell culture supernatant by affinity chromatography
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Isotype
- IgG
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Application Notes
- ELISA 1:5000-10000, Flow Cyt 1:100
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Restrictions
- For Research Use only
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Format
- Liquid
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Storage
- -20 °C,-80 °C
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Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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Expiry Date
- 12 months
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- Neuregulin 1 (NRG1)
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Alternative Name
- NRG1
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Background
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ARIA, GGF, GGF2, HGL, HRG, HRG1, HRGA, MST131, MSTP131, NDF, NRG1-IT2, SMDF,
Description: The protein encoded by this gene is a membrane glycoprotein that mediates cell-cell signaling and plays a critical role in the growth and development of multiple organ systems. An extraordinary variety of different isoforms are produced from this gene through alternative promoter usage and splicing. These isoforms are expressed in a tissue-specific manner and differ significantly in their structure, and are classified as types I, II, III, IV, V and VI. Dysregulation of this gene has been linked to diseases such as cancer, schizophrenia, and bipolar disorder (BPD). -
UniProt
- Q02297
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Pathways
- RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation
Target
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