Melanoma gp100 antibody

Catalog No. ABIN7490666

The Rabbit Chimeric anti-Melanoma gp100 antibody has been validated for FACS. It is suitable to detect Melanoma gp100 in samples from Human.

Quick Overview for Melanoma gp100 antibody (ABIN7490666)

Target: Melanoma gp100 (PMEL) (Premelanosome Protein (PMEL))

Fragment: Fc fragment

Reactivity: Human

Host: Rabbit

Clonality: Chimeric

Conjugate: This Melanoma gp100 antibody is un-conjugated

Application: Flow Cytometry (FACS)

Product Details anti-Melanoma gp100 Antibody

Characteristics: Rabbit/Human Fc chimeric IgG1

Purification: Purified from cell culture supernatant by affinity chromatography

Isotype: IgG1

Application Details

Application Notes: Flow Cyt  1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Expiry Date: 12 months

Target Details for Melanoma gp100

Target: Melanoma gp100 (PMEL) (Premelanosome Protein (PMEL))

Alternative Name: PMEL

Background: D12S53E, gp100, ME20, ME20-M, ME20M, P1, P100, PMEL17, SI, SIL, SILV,
Description: This gene encodes a melanocyte-specific type I transmembrane glycoprotein. The encoded protein is enriched in melanosomes, which are the melanin-producing organelles in melanocytes, and plays an essential role in the structural organization of premelanosomes. This protein is involved in generating internal matrix fibers that define the transition from Stage I to Stage II melanosomes. This protein undergoes a complex pattern of prosttranslational processing and modification that is essential to the proper functioning of the protein. A secreted form of this protein that is released by proteolytic ectodomain shedding may be used as a melanoma-specific serum marker. Alternate splicing results in multiple transcript variants.

UniProt: P40967