GDF15
Reactivity: Human
WB, ELISA, IHC, ICC, IF
Host: Rabbit
Polyclonal
unconjugated
Application Notes
Flow Cyt 1:100
Restrictions
For Research Use only
Format
Liquid
Storage
-20 °C,-80 °C
Storage Comment
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Expiry Date
12 months
Target
GDF15
(Growth Differentiation Factor 15 (GDF15))
Alternative Name
GDF15
Background
GDF-15, MIC-1, MIC1, NAG-1, PDF, PLAB, PTGFB, Description: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. The protein is expressed in a broad range of cell types, acts as a pleiotropic cytokine and is involved in the stress response program of cells after cellular injury. Increased protein levels are associated with disease states such as tissue hypoxia, inflammation, acute injury and oxidative stress. [provided by RefSeq, Aug 2016]