Recombinant YAP1 antibody

Catalog No. ABIN7490882

The Human Chimeric anti-YAP1 antibody is suitable to detect YAP1 in samples from Human. It has been validated for FACS.

Quick Overview for Recombinant YAP1 antibody (ABIN7490882)

Target: YAP1 (Yes-Associated Protein 1 (YAP1))

Antibody Type: Recombinant Antibody

Fragment: Fc fragment

Reactivity: Human

Host: Human, Rabbit

Clonality: Chimeric

Conjugate: This YAP1 antibody is un-conjugated

Application: Flow Cytometry (FACS)

Clone: DMC495

Product Details anti-YAP1 Antibody

Purpose: Anti-YAP1 antibody(DMC495), IgG1 Chimeric mAb

Purification: Purified from cell culture supernatant by affinity chromatography

Isotype: IgG1

Application Details

Application Notes: Flow Cyt 1:100

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please see Certificate of Analysis for specific instructions of reconstitution.

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Expiry Date: 12 months

Target Details for YAP1

Target: YAP1 (Yes-Associated Protein 1 (YAP1))

Alternative Name: YAP1

Background: COB1, YAP, YAP2, YAP65, YKI,
Description: This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms.

UniProt: P46937

Pathways: MAPK Signaling, Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha