HBEGF antibody

Catalog No. ABIN7490902

This Rabbit Chimeric antibody specifically detects HBEGF in FACS. It exhibits reactivity toward Human.

Quick Overview for HBEGF antibody (ABIN7490902)

Target: HBEGF (Heparin-Binding EGF-Like Growth Factor (HBEGF))

Fragment: Fc fragment

Reactivity: Human

Host: Rabbit

Clonality: Chimeric

Conjugate: This HBEGF antibody is un-conjugated

Application: Flow Cytometry (FACS)

Product Details anti-HBEGF Antibody

Characteristics: Rabbit/Human Fc chimeric IgG1

Purification: Purified from cell culture supernatant by affinity chromatography

Isotype: IgG1

Application Details

Application Notes: Flow Cyt 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Expiry Date: 12 months

Target Details for HBEGF

Target: HBEGF (Heparin-Binding EGF-Like Growth Factor (HBEGF))

Alternative Name: HBEGF

Background: DTR, DTS, DTSF, HEGFL,
Description: Growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. Required for normal cardiac valve formation and normal heart function. Promotes smooth muscle cell proliferation. May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor.[UniProtKB/Swiss-Prot Function]

UniProt: Q99075

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway