KIT antibody (Biotin)
Quick Overview for KIT antibody (Biotin) (ABIN7456662)
Target
See all KIT AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Isotype
- IgG2b, kappa
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Application Notes
- For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10^6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
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Comment
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Matching Isotype Control: Biotin Rat IgG2b, κ Isotype Control (ABIN7469857)
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Restrictions
- For Research Use only
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Concentration
- 0.5 mg/mL
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Buffer
- PBS with 0.05 % Proclin300, 1 % BSA
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Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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Storage Comment
- Store at 2~8°C. Do not freeze.
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- KIT (Mast/stem Cell Growth Factor Receptor (KIT))
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Alternative Name
- CD117
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Background
- Mast/stem cell growth factor receptor Kit,Kit,SCFR,Proto-oncogene c-Kit,Tyrosine-protein kinase Kit,CD117,CD117 is a 145 kD immunoglobulin superfamily member also known as c-Kit and stem cell factor receptor (SCFR). It is a transmembrane tyrosine-kinase receptor that binds the c-Kit ligand (also known as steel factor, stem cell factor, and mast cell growth factor). CD117 is expressed on hematopoietic stem cells (including multipotent hematopoietic stem cells, progenitors committed to myeloid and/or erythroid lineages, and T and B cell precursors), mast cells, and acute myeloid leukemia (AML) cells. CD117 interaction with its ligand is critical for the development of hematopoietic stem cells.
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Gene ID
- 16590
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UniProt
- P05532
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Pathways
- RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Sensory Perception of Sound, Stem Cell Maintenance, Production of Molecular Mediator of Immune Response, Regulation of long-term Neuronal Synaptic Plasticity
Target
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