CD25 antibody (PE-Cy5)

Catalog No. ABIN7457322

This Mouse Monoclonal antibody specifically detects CD25 in FACS. It exhibits reactivity toward Human.

Quick Overview for CD25 antibody (PE-Cy5) (ABIN7457322)

Target: CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD25 antibody is conjugated to PE-Cy5

Application: Flow Cytometry (FACS)

Clone: BC96

Product Details anti-CD25 Antibody (PE-Cy5)

Isotype: IgG1, kappa

Application Details

Application Notes: The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Comment:

Matching Isotype Control: PE/Cyanine5 Mouse IgG1, κ Isotype Control

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.05 % Proclin300, 1 % BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Target Details for CD25

Target: CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))

Alternative Name: CD25

Background: Interleukin-2 receptor subunit alpha,IL2RA,IL-2 receptor subunit alpha,IL-2-RA,IL-2R subunit alpha,IL2-RA,TAC antigen,p55,p55,CD25 is a 55 kD type I transmembrane glycoprotein also known as the low affinity IL-2 receptor α chain or Tac. It is expressed on progenitor lymphocytes, activated T and B cells, and activated monocytes/macrophages. CD25 is also expressed on a subset of non-stimulated CD4+ T cells termed T regulatory cells. CD25 associates with the IL-2 receptor β (CD122) and common γ chains (CD132) to form the high affinity IL-2R complex.

Gene ID: 3559

UniProt: P01589

Pathways: JAK-STAT Signaling, Growth Factor Binding, Activated T Cell Proliferation