IL2RG antibody

Catalog No. ABIN7457856

This Rat Monoclonal antibody specifically detects IL2RG in FACS. It exhibits reactivity toward Mouse.

Quick Overview for IL2RG antibody (ABIN7457856)

Target: IL2RG (Interleukin 2 Receptor, gamma (IL2RG))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This IL2RG antibody is un-conjugated

Application: Flow Cytometry (FACS)

Clone: 3E12

Product Details anti-IL2RG Antibody

Purification: Purified

Sterility: 0.2 μm filtered

Endotoxin Level: Low Endotoxin: Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.

Isotype: IgG2b, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Matching Isotype Control: AF/LE Purified Rat IgG2b, κ Isotype Control (ABIN7469855)

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE)

Preservative: Azide free

Storage: 4 °C

Storage Comment: Store at 2~8°C. Do not freeze.

Target Details for IL2RG

Target: IL2RG (Interleukin 2 Receptor, gamma (IL2RG))

Alternative Name: CD132

Background: Cytokine receptor common subunit gamma,Il2rg,Interleukin-2 receptor subunit gamma,IL-2 receptor subunit gamma,IL-2R subunit gamma,IL-2RG,gammaC,p64,CD132,CD132 is a 64-70 kD type I transmembrane glycoprotein of the Ig superfamily, and is also known as common γ chain (γc) or IL-2 receptor γ subunit. It is expressed broadly on T- and B-lymphocytes, NK cells, monocytes, and granulocytes. CD132 is an essential component of cytokine receptors for IL-2, IL-4, IL-7, IL-9, IL-15, and IL-21. Ligand binding induces tyrosine phosphorylation and initiates signaling through a JAK/STAT pathway. CD132 mutation results in X-linked severe combined immune deficiency (XSCID).

Gene ID: 16186

UniProt: P34902

Pathways: JAK-STAT Signaling, Growth Factor Binding