HIST2H2AA3 antibody (acLys5)

Catalog No. ABIN7464449

Product Details anti-HIST2H2AA3 Antibody

Target: HIST2H2AA3 (Histone Cluster 2, H2aa3 (HIST2H2AA3))

Binding Specificity: acLys5

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This HIST2H2AA3 antibody is un-conjugated

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human, Mouse, Rat

Purification: Affinity purified by Protein G.

Immunogen: Carrier-protein conjugated synthetic peptide surrounding acetyl Lys5 of human Histone H2A. The exact sequence is proprietary.

Clone: GT1262

Isotype: IgG3

Application Details

Application Notes: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: HeLa , HeLa (0.4 μM Trichoststin A for 18 hr)

Validation: Orthogonal

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.96 mg/mL

Buffer: PBS, No Preservative

Preservative: Without preservative

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for HIST2H2AA3

Target: HIST2H2AA3 (Histone Cluster 2, H2aa3 (HIST2H2AA3))

Alternative Name: histone cluster 2, H2aa3 (HIST2H2AA3 Products)

Synonyms: H2A antibody, H2A.2 antibody, H2A/O antibody, H2A/q antibody, H2AFO antibody, H2a-615 antibody, HIST2H2AA antibody, Hist2h2aa antibody, Hist2h2aa1 antibody, histone cluster 2 H2A family member a3 antibody, histone cluster 2 H2A family member A3 antibody, HIST2H2AA3 antibody, Hist2h2aa3 antibody

Background: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2A family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated, this record represents the centromeric copy. [provided by RefSeq]

Molecular Weight: 14 kDa

Gene ID: 8337

Pathways: Telomere Maintenance