HIST2H2AA3 antibody (acLys5)

Catalog No. ABIN7464478

The Rabbit Polyclonal anti-HIST2H2AA3 antibody has been validated for WB, ICC, IP, IF and DB. It is suitable to detect HIST2H2AA3 in samples from Human.

Quick Overview for HIST2H2AA3 antibody (acLys5) (ABIN7464478)

Target: HIST2H2AA3 (Histone Cluster 2, H2aa3 (HIST2H2AA3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HIST2H2AA3 antibody is un-conjugated

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunoprecipitation (IP), Immunofluorescence (IF), Dot Blot (DB)

Product Details anti-HIST2H2AA3 Antibody

Binding Specificity: acLys5

Cross-Reactivity: Human

Purification: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide surrounding acetyl Lys5 of human Histone H2A. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:1000-1:20000. ICC/IF: 1:100-1:1000. IP: 1:100-1:10000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: HeLa (0.012% DMSO treatment for 18 hr) , HeLa (0.4 μM Trichostatin A treatment for 18 hr)

Validation: Orthogonal

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for HIST2H2AA3

Target: HIST2H2AA3 (Histone Cluster 2, H2aa3 (HIST2H2AA3))

Alternative Name: histone cluster 2, H2aa3

Background: H2a-615 Antibody , H2A/q Antibody , H2A Antibody , HIST2H2AA3 Antibody , histone cluster 2 , H2aa3 Antibody , H2AFO Antibody , H2A/O Antibody , HIST2H2AA Antibody , H2A.2 Antibody,Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2A family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated, this record represents the centromeric copy. [provided by RefSeq]

Gene ID: 8337

Pathways: Telomere Maintenance