Serotonin Receptor 2B antibody (N-Term)

Catalog No. ABIN7464797

This anti-Serotonin Receptor 2B antibody is a Rabbit Polyclonal antibody detecting Serotonin Receptor 2B in WB. Suitable for Human.

Quick Overview for Serotonin Receptor 2B antibody (N-Term) (ABIN7464797)

Target: Serotonin Receptor 2B (HTR2B)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Serotonin Receptor 2B antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Serotonin Receptor 2B Antibody

Binding Specificity: N-Term

Cross-Reactivity: Human, Mouse

Purification: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human 5-HT2B receptor. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: mouse liver , SH-SY5Y membrane extract

Validation: Orthogonal

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 2.29 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for Serotonin Receptor 2B

Target: Serotonin Receptor 2B (HTR2B)

Alternative Name: 5-hydroxytryptamine receptor 2B

Background: 5-hydroxytryptamine receptor 2B , 5-HT(2B) , 5-HT-2B , 5-HT2B,Multiple receptor subtypes of serotonin neurotransmitters with multiple physiologic functions have been recognized. The 5-HT-2 receptors mediate many of the central and peripheral physiologic functions of serotonin. Cardiovascular effects include contraction of blood vessels and shape changes in platelets, central nervous system effects include neuronal sensitization to tactile stimuli and mediation of hallucinogenic effects of phenylisopropylamine hallucinogens.[supplied by OMIM]

Molecular Weight: 54 kDa

Gene ID: 3357

UniProt: P41595

Pathways: JAK-STAT Signaling, Inositol Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of Carbohydrate Metabolic Process