GHSR antibody (N-Term)

Catalog No. ABIN7464860

The Rabbit Polyclonal anti-GHSR antibody (ABIN7464860) specifically detects GHSR in WB, IHC (p), ICC and IF. The antibody is reactive with Human samples.

Quick Overview for GHSR antibody (N-Term) (ABIN7464860)

Target: GHSR (Growth Hormone Secretagogue Receptor (GHSR))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GHSR antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (IF)

Grade: KO Validated

Product Details anti-GHSR Antibody

Binding Specificity: N-Term

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human GHS-R1. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: NT2D1 , PC-3 , U87-MG , SK-N-SH , mouse hypothalamus , mouse brain , rat brain

Validation: KO/KD, Orthogonal

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for GHSR

Target: GHSR (Growth Hormone Secretagogue Receptor (GHSR))

Alternative Name: growth hormone secretagogue receptor

Background: Growth hormone secretagogue receptor , GHDP,This gene encodes a member of the G-protein coupled receptor family. The encoded protein may play a role in energy homeostasis and regulation of body weight. Two identified transcript variants are expressed in several tissues and are evolutionary conserved in fish and swine. One transcript, 1a, excises an intron and encodes the functional protein, this protein is the receptor for the Ghrelin ligand and defines a neuroendocrine pathway for growth hormone release. The second transcript (1b) retains the intron and does not function as a receptor for Ghrelin, however, it may function to attenuate activity of isoform 1a. [provided by RefSeq]

Molecular Weight: 41 kDa

Gene ID: 2693

UniProt: Q92847

Pathways: Hormone Transport, Negative Regulation of Hormone Secretion, Feeding Behaviour