GLIS3 antibody (C-Term)

Catalog No. ABIN7465364

This anti-GLIS3 antibody is a Rabbit Polyclonal antibody detecting GLIS3 in WB. Suitable for Human.

Quick Overview for GLIS3 antibody (C-Term) (ABIN7465364)

Target: GLIS3 (GLIS Family Zinc Finger 3 (GLIS3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GLIS3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GLIS3 Antibody

Binding Specificity: C-Term

Cross-Reactivity: Human

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human GLIS3. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: A431

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.87 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for GLIS3

Target: GLIS3 (GLIS Family Zinc Finger 3 (GLIS3))

Alternative Name: GLIS family zinc finger 3

Background: GLIS family zinc finger 3 , NDH , ZNF515,This gene is a member of the GLI-similar zinc finger protein family and encodes a nuclear protein with five C2H2-type zinc finger domains. This protein functions as both a repressor and activator of transcription and is specifically involved in the development of pancreatic beta cells, the thyroid, eye, liver and kidney. Mutations in this gene have been associated with neonatal diabetes and congenital hypothyroidism (NDH). Alternatively spliced variants that encode different protein isoforms have been described but the full-length nature of only two have been determined. [provided by RefSeq]

Molecular Weight: 84 kDa

Gene ID: 169792

UniProt: Q8NEA6