MRPL40 antibody

Catalog No. ABIN7465585

The Rabbit Polyclonal anti-MRPL40 antibody has been validated for WB. It is suitable to detect MRPL40 in samples from Human.

Quick Overview for MRPL40 antibody (ABIN7465585)

Target: MRPL40 (Mitochondrial Ribosomal Protein L40 (MRPL40))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRPL40 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MRPL40 Antibody

Cross-Reactivity: Human, Rat

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human MRPL40. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: A549 , H1299 , HCT-116

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.75 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for MRPL40

Target: MRPL40 (Mitochondrial Ribosomal Protein L40 (MRPL40))

Alternative Name: mitochondrial ribosomal protein L40

Background: Mitochondrial ribosomal protein L40 , L40mt , MRP-L22 , MRP-L40 , MRPL22 , NLVCF , URIM,Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Deletions in this gene may contribute to the etiology of velo-cardio-facial syndrome and DiGeorge syndrome. [provided by RefSeq]

Molecular Weight: 24 kDa

Gene ID: 64976

UniProt: Q9NQ50