Factor XI antibody (C-Term)
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- Target See all Factor XI (F11) Antibodies
- Factor XI (F11) (Coagulation Factor XI (F11))
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Binding Specificity
- C-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Factor XI antibody is un-conjugated
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Application
- Western Blotting (WB)
- Cross-Reactivity
- Human, Mouse
- Purification
- Purified by antigen-affinity chromatography.
- Immunogen
- Recombinant protein encompassing a sequence within the C-terminus region of human Factor XI. The exact sequence is proprietary.
- Isotype
- IgG
- Top Product
- Discover our top product F11 Primary Antibody
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- Application Notes
- WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- Comment
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Positive Control: A549 , human plasma
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.67 mg/mL
- Buffer
- 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
- Preservative
- Thimerosal (Merthiolate)
- Precaution of Use
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Target
- Factor XI (F11) (Coagulation Factor XI (F11))
- Alternative Name
- coagulation factor XI (F11 Products)
- Synonyms
- FXI antibody, 1600027G01Rik antibody, AI503996 antibody, Cf11 antibody, LRRGT00086 antibody, coagulation factor XI antibody, F11 antibody, CpipJ_CPIJ000593 antibody, CpipJ_CPIJ001060 antibody, CpipJ_CPIJ002752 antibody, CpipJ_CPIJ003631 antibody, CpipJ_CPIJ004041 antibody, CpipJ_CPIJ004093 antibody
- Background
- Coagulation factor XI , FXI , PTA,This gene encodes coagulation factor XI of the blood coagulation cascade. This protein is present in plasma as a zymogen, which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI, an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains, resulting in activated factor XIa, a serine protease composed of two heavy and two light chains held together by disulfide bonds. This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX. Defects in this factor lead to Rosenthal syndrome, a blood coagulation abnormality. [provided by RefSeq]
- Molecular Weight
- 70 kDa
- Gene ID
- 2160
- UniProt
- P03951
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