POLD1 antibody (AA 1-140)

Catalog No. ABIN7465932

This Mouse Monoclonal antibody specifically detects POLD1 in WB and IHC (p). It exhibits reactivity toward Human.

Quick Overview for POLD1 antibody (AA 1-140) (ABIN7465932)

Target: POLD1 (Polymerase (DNA Directed), delta 1, Catalytic Subunit 125kDa (POLD1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This POLD1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 6196

Product Details anti-POLD1 Antibody

Binding Specificity: AA 1-140

Cross-Reactivity: Human

Purification: Protein G purified

Immunogen: Recombinant protein encoding amino acids 1-140 of the large subunit of human DNA polymerase d.

Isotype: IgG1

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: HeLa

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.22 mg/mL

Buffer: PBS, No Preservative

Preservative: Without preservative

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for POLD1

Target: POLD1 (Polymerase (DNA Directed), delta 1, Catalytic Subunit 125kDa (POLD1))

Alternative Name: DNA polymerase delta 1

Background: DNA polymerase delta 1, catalytic subunit , CDC2 , CRCS10 , MDPL , POLD,This gene encodes the 125- kDa catalytic subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 6. [provided by RefSeq, Mar 2012]

Molecular Weight: 124 kDa

Gene ID: 5424

UniProt: P28340

Pathways: Telomere Maintenance, DNA Damage Repair, DNA Replication, Chromatin Binding, Synthesis of DNA