TBL1X antibody (C-Term)

Catalog No. ABIN7466008

The Rabbit Polyclonal anti-TBL1X antibody has been validated for WB. It is suitable to detect TBL1X in samples from Human.

Quick Overview for TBL1X antibody (C-Term) (ABIN7466008)

Target: TBL1X (Transducin (Beta)-Like 1X-Linked (TBL1X))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TBL1X antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TBL1X Antibody

Binding Specificity: C-Term

Cross-Reactivity: Human

Purification: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human TBL1X. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: HeLaS3

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.94 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for TBL1X

Target: TBL1X (Transducin (Beta)-Like 1X-Linked (TBL1X))

Alternative Name: transducin beta like 1 X-linked

Background: Transducin beta like 1 X-linked , EBI , SMAP55 , TBL1,The protein encoded by this gene has sequence similarity with members of the WD40 repeat-containing protein family. The WD40 group is a large family of proteins, which appear to have a regulatory function. It is believed that the WD40 repeats mediate protein-protein interactions and members of the family are involved in signal transduction, RNA processing, gene regulation, vesicular trafficking, cytoskeletal assembly and may play a role in the control of cytotypic differentiation. This encoded protein is found as a subunit in corepressor SMRT (silencing mediator for retinoid and thyroid receptors) complex along with histone deacetylase 3 protein. This gene is located adjacent to the ocular albinism gene and it is thought to be involved in the pathogenesis of the ocular albinism with late-onset sensorineural deafness phenotype. Four transcript variants encoding two different isoforms have been found for this gene. This gene is highly similar to the Y chromosome TBL1Y gene. [provided by RefSeq]

Molecular Weight: 62 kDa

Gene ID: 6907

UniProt: O60907

Pathways: Sensory Perception of Sound, Regulation of Lipid Metabolism by PPARalpha