SREBF chaperone antibody (C-Term)

Catalog No. ABIN7466147

This anti-SREBF chaperone antibody is a Rabbit Polyclonal antibody detecting SREBF chaperone in WB and IHC (p). Suitable for Human.

Quick Overview for SREBF chaperone antibody (C-Term) (ABIN7466147)

Target: SREBF chaperone (SCAP)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SREBF chaperone antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-SREBF chaperone Antibody

Binding Specificity: C-Term

Cross-Reactivity: Human, Mouse

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human SCAP. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: HepG2 , MCF-7

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.43 mg/mL

Buffer: 1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for SREBF chaperone

Target: SREBF chaperone (SCAP)

Alternative Name: SREBF chaperone

Background: SREBF chaperone,This gene encodes a protein with a sterol sensing domain (SSD) and seven WD domains. In the presence of cholesterol, this protein binds to sterol regulatory element binding proteins (SREBPs) and mediates their transport from the ER to the Golgi. The SREBPs are then proteolytically cleaved and regulate sterol biosynthesis. [provided by RefSeq]

Molecular Weight: 140 kDa

Gene ID: 22937

UniProt: Q12770

Pathways: SARS-CoV-2 Protein Interactome