SREBF chaperone antibody (AA 251-350)

Catalog No. ABIN750283

Product Details anti-SREBF chaperone Antibody

Target: SREBF chaperone (SCAP)

Binding Specificity: AA 251-350

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SREBF chaperone antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Dog,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SCAP

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for SREBF chaperone

Target: SREBF chaperone (SCAP)

Alternative Name: SCAP/SREBF chaperone protein (SCAP Products)

Synonyms: 9530044G19 antibody, mKIAA0199 antibody, SREBF chaperone antibody, SREBF chaperone S homeolog antibody, SCAP antibody, Scap antibody, scap.S antibody

Background:

Synonyms: KIAA0199, SCAP, SCAP_HUMAN, SREBF chaperone, SREBF chaperone protein, SREBP cleavage activating protein, SREBP cleavage-activating protein, Sterol regulatory element binding protein cleavage-activating protein, Sterol regulatory element-binding protein cleavage-activating protein.

Background: SCAP is an escort protein required for cholestrol and lipid homeostasis. Cholesterol homeostasis in animal cells is achieved by regulated cleavage of SREBPs, membrane-bound transcription factors. SCAP forms a complex with SREBPs in order to release the active domains of SREBPs.

Gene ID: 22937

UniProt: Q12770

Pathways: SARS-CoV-2 Protein Interactome