HNF1A antibody

Catalog No. ABIN7466158

The Mouse Monoclonal anti-HNF1A antibody has been validated for WB and IHC (p). It is suitable to detect HNF1A in samples from Human.

Quick Overview for HNF1A antibody (ABIN7466158)

Target: HNF1A (HNF1 Homeobox A (HNF1A))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This HNF1A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: GT4110

Product Details anti-HNF1A Antibody

Cross-Reactivity: Human, Mouse

Purification: Affinity purified by Protein G.

Immunogen: Recombinant protein encompassing a sequence within the center region of human HNF1 alpha. The exact sequence is proprietary.

Isotype: IgG2a

Application Details

Application Notes: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: HepG2 , mouse liver

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, No Preservative

Preservative: Without preservative

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for HNF1A

Target: HNF1A (HNF1 Homeobox A (HNF1A))

Alternative Name: HNF1 homeobox A

Background: HNF1 homeobox A , HNF-1A , HNF1 , HNF4A , IDDM20 , LFB1 , MODY3 , TCF-1 , TCF1,The protein encoded by this gene is a transcription factor required for the expression of several liver-specific genes. The encoded protein functions as a homodimer and binds to the inverted palindrome 5'-GTTAATNATTAAC-3'. Defects in this gene are a cause of maturity onset diabetes of the young type 3 (MODY3) and also can result in the appearance of hepatic adenomas. [provided by RefSeq]

Molecular Weight: 67 kDa

Gene ID: 6927

UniProt: P20823

Pathways: Hormone Transport, Carbohydrate Homeostasis