ALKBH3 antibody

Catalog No. ABIN7467388

The Rabbit Polyclonal anti-ALKBH3 antibody is suitable to detect ALKBH3 in samples from Human. It has been validated for WB.

Quick Overview for ALKBH3 antibody (ABIN7467388)

Target: ALKBH3 (AlkB, Alkylation Repair Homolog 3 (ALKBH3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ALKBH3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ALKBH3 Antibody

Cross-Reactivity: Rat

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human ALKBH3. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: rat stomach

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 2.06 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for ALKBH3

Target: ALKBH3 (AlkB, Alkylation Repair Homolog 3 (ALKBH3))

Alternative Name: alkB homolog 3, alpha-ketoglutaratedependent dioxygenase

Background: AlkB homolog 3, alpha-ketoglutaratedependent dioxygenase , ABH3 , DEPC-1 , DEPC1 , PCA1 , hABH3,The Escherichia coli AlkB protein protects against the cytotoxicity of methylating agents by repair of the specific DNA lesions generated in single-stranded DNA. ALKBH2 (MIM 610602) and ALKBH3 are E. coli AlkB homologs that catalyze the removal of 1-methyladenine and 3-methylcytosine (Duncan et al., 2002 [PubMed 12486230]).[supplied by OMIM]

Molecular Weight: 33 kDa

Gene ID: 221120

UniProt: Q96Q83

Pathways: DNA Damage Repair