AKAP8L antibody

Catalog No. ABIN7467916

The Rabbit Polyclonal anti-AKAP8L antibody has been validated for WB, ELISA and IP. It is suitable to detect AKAP8L in samples from Human.

Quick Overview for AKAP8L antibody (ABIN7467916)

Target: AKAP8L (A Kinase (PRKA) Anchor Protein 8-Like (AKAP8L))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AKAP8L antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Grade: KO Validated

Product Details anti-AKAP8L Antibody

Specificity: Knockdown/Knockout validation was supported by references (PMID:26990993)

Cross-Reactivity: Human

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human AKAP8L. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:1000-1:10000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: 293T Validation: KO/KD

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for AKAP8L

Target: AKAP8L (A Kinase (PRKA) Anchor Protein 8-Like (AKAP8L))

Alternative Name: A-kinase anchoring protein 8 like

Background:

Synonyms: A-kinase anchoring protein 8 like , HA95 , HAP95 , NAKAP , NAKAP95

Background: Could play a role in constitutive transport element (CTE)-mediated gene expression. Does not seem to be implicated in the binding of regulatory subunit II of PKA. May be involved in nuclear envelope breakdown and chromatin condensation. May regulate the initiation phase of DNA replication when associated with TMPO-beta.

Molecular Weight: 72 kDa

Gene ID: 26993

UniProt: Q9ULX6

Pathways: SARS-CoV-2 Protein Interactome