RAD1 antibody (N-Term)

Catalog No. ABIN7468121

Product Details anti-RAD1 Antibody

Target: RAD1 (Cell Cycle Checkpoint Protein RAD1 (RAD1))

Binding Specificity: N-Term

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This RAD1 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Human

Purification: Protein G purified

Immunogen: Amino terminal fragment of human Rad1 purified from E. coli.

Clone: 4126

Isotype: IgG2a

Application Details

Application Notes: WB: 1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: 293T , A431 , HeLa , HepG2

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, No Preservative

Preservative: Without preservative

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for RAD1

Target: RAD1 (Cell Cycle Checkpoint Protein RAD1 (RAD1))

Alternative Name: RAD1 checkpoint DNA exonuclease (RAD1 Products)

Synonyms: HRAD1 antibody, REC1 antibody, zgc:56502 antibody, zgc:77779 antibody, RAD1 antibody, xrad1 antibody, DKFZp459H1127 antibody, RAD1 checkpoint DNA exonuclease antibody, RAD1 homolog (S. pombe) antibody, RAD1 antibody, Rad1 antibody, rad1 antibody

Background:

Synonyms: RAD1 checkpoint DNA exonuclease , HRAD1 , REC1

Background: This gene encodes a component of a heterotrimeric cell cycle checkpoint complex, known as the 9-1-1 complex, that is activated to stop cell cycle progression in response to DNA damage or incomplete DNA replication. The 9-1-1 complex is recruited by RAD17 to affected sites where it may attract specialized DNA polymerases and other DNA repair effectors. Alternatively spliced transcript variants of this gene have been described. [provided by RefSeq, Jan 2009]

Molecular Weight: 32 kDa

Gene ID: 5810

UniProt: O60671

Pathways: M Phase