CLN5 antibody

Catalog No. ABIN7468129

The Rabbit Polyclonal anti-CLN5 antibody has been validated for WB. It is suitable to detect CLN5 in samples from Human.

Quick Overview for CLN5 antibody (ABIN7468129)

Target: CLN5 (Ceroid-Lipofuscinosis, Neuronal 5 (CLN5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CLN5 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CLN5 Antibody

Cross-Reactivity: Human

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human CLN5. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: 293T , A431 , HeLa , HepG2

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.13 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for CLN5

Target: CLN5 (Ceroid-Lipofuscinosis, Neuronal 5 (CLN5))

Alternative Name: CLN5 intracellular trafficking protein

Background:

Synonyms: CLN5 intracellular trafficking protein

Background: This gene is one of eight which have been associated with neuronal ceroid lipofuscinoses (NCL). Also referred to as Batten disease, NCL comprises a class of autosomal recessive, neurodegenerative disorders affecting children. The genes responsible likely encode proteins involved in the degradation of post-translationally modified proteins in lysosomes. The primary defect in NCL disorders is thought to be associated with lysosomal storage function.

Molecular Weight: 41 kDa

Gene ID: 1203

UniProt: O75503