COPS6 antibody

Catalog No. ABIN7468168

The Rabbit Polyclonal anti-COPS6 antibody has been validated for WB. It is suitable to detect COPS6 in samples from Human.

Quick Overview for COPS6 antibody (ABIN7468168)

Target: COPS6 (COP9 Signalosome Complex Subunit 6 (COPS6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COPS6 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-COPS6 Antibody

Cross-Reactivity: Human

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human CSN6. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.88 mg/mL

Buffer: 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for COPS6

Target: COPS6 (COP9 Signalosome Complex Subunit 6 (COPS6))

Alternative Name: COP9 signalosome subunit 6

Background:

Synonyms: COP9 signalosome subunit 6 , CSN6 , MOV34-34KD

Background: The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein belongs to translation initiation factor 3 (eIF3) superfamily. It is involved in the regulation of cell cycle and likely to be a cellular cofactor for HIV-1 accessory gene product Vpr. [provided by RefSeq]

Molecular Weight: 36 kDa

Gene ID: 10980

UniProt: Q7L5N1

Pathways: Cell Division Cycle