DEK antibody (C-Term)
Quick Overview for DEK antibody (C-Term) (ABIN7468238)
Target
See all DEK AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- C-Term
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Cross-Reactivity
- Human
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Purification
- Purified by antigen-affinity chromatography.
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Immunogen
- Recombinant protein encompassing a sequence within the C-terminus of human DEK. The exact sequence is proprietary.
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Isotype
- IgG
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Application Notes
- WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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Comment
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Positive Control: MCF-7 nuclear extract Validation: Orthogonal
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.83 mg/mL
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Buffer
- 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
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Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- DEK (DEK Oncogene (DEK))
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Alternative Name
- DEK proto-oncogene
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Background
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Synonyms: DEK proto-oncogene , D6S231E
Background: This gene encodes a protein with one SAP domain. This protein binds to cruciform and superhelical DNA and induces positive supercoils into closed circular DNA, and is also involved in splice site selection during mRNA processing. Chromosomal aberrations involving this region, increased expression of this gene, and the presence of antibodies against this protein are all associated with various diseases. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
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Molecular Weight
- 43 kDa
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Gene ID
- 7913
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UniProt
- P35659
Target
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