Derlin-3 antibody

Catalog No. ABIN7468254

This Rabbit Polyclonal antibody specifically detects Derlin-3 in WB. It exhibits reactivity toward Human.

Quick Overview for Derlin-3 antibody (ABIN7468254)

Target: Derlin-3 (DERL3) (Der1-Like Domain Family, Member 3 (DERL3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Derlin-3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Derlin-3 Antibody

Cross-Reactivity: Human

Purification: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human DERL3. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for Derlin-3

Target: Derlin-3 (DERL3) (Der1-Like Domain Family, Member 3 (DERL3))

Alternative Name: derlin 3

Background:

Synonyms: derlin 3 , C22orf14 , IZP6 , LLN2 , derlin-3

Background: The protein encoded by this gene belongs to the derlin family, and resides in the endoplasmic reticulum (ER). Proteins that are unfolded or misfolded in the ER must be refolded or degraded to maintain the homeostasis of the ER. This protein appears to be involved in the degradation of misfolded glycoproteins in the ER. Several alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq]

Molecular Weight: 27 kDa

Gene ID: 91319

UniProt: Q96Q80

Pathways: ER-Nucleus Signaling