TUB antibody

Catalog No. ABIN7469093

This anti-TUB antibody is a Rabbit Polyclonal antibody detecting TUB in WB, IHC (p), ICC and IF. Suitable for Human.

Quick Overview for TUB antibody (ABIN7469093)

Target: TUB (Tubby Homolog (TUB))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TUB antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (IF)

Product Details anti-TUB Antibody

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human Tub. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: NT2D1 , PC-3 , U87-MG , SK-N-SH , Neuro2A , GL261

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for TUB

Target: TUB (Tubby Homolog (TUB))

Alternative Name: tubby bipartite transcription factor

Background:

Synonyms: tubby bipartite transcription factor , RDOB , rd5

Background: This gene encodes a member of the Tubby family of bipartite transcription factors. The encoded protein may play a role in obesity and sensorineural degradation. The crystal structure has been determined for a similar protein in mouse, and it functions as a membrane-bound transcription regulator that translocates to the nucleus in response to phosphoinositide hydrolysis. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq]

Molecular Weight: 56 kDa

Gene ID: 7275

UniProt: P50607

Pathways: RTK Signaling, Sensory Perception of Sound