FANCC antibody (C-Term)

Catalog No. ABIN7469358

This Rabbit Polyclonal antibody specifically detects FANCC in WB. It exhibits reactivity toward Human.

Quick Overview for FANCC antibody (C-Term) (ABIN7469358)

Target: FANCC (Fanconi Anemia, Complementation Group C (FANCC))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FANCC antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FANCC Antibody

Binding Specificity: C-Term

Cross-Reactivity: Human

Purification: Affinity purified with antigen.

Immunogen: A synthetic peptide corresponding to the C-terminal 15 amino acids, conjugated to a carrier protein

Isotype: IgG

Application Details

Application Notes: For WB: Use at a dilution of 1:500 with TBST plus 3 % powdered milk. Optimal dilutions/concentrations should be determined by the researhcer.

Comment:

Positive Control: HeLa nuclear cell lysate

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS pH 7.2, No Preservative

Preservative: Without preservative

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for FANCC

Target: FANCC (Fanconi Anemia, Complementation Group C (FANCC))

Alternative Name: FANCC

Background:

Synonyms: FA complementation group C , FA3 , FAC , FACC

Background: The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity, they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group C. [provided by RefSeq, Jul 2008]

Molecular Weight: 63 kDa

Gene ID: 2176

UniProt: Q00597

Pathways: DNA Damage Repair