Recombinant Angiotensin II antibody

Catalog No. ABIN7487680

This anti-Angiotensin II antibody is a Rabbit Chimeric antibody detecting Angiotensin II in . Suitable for Rat.

Quick Overview for Recombinant Angiotensin II antibody (ABIN7487680)

Target: Angiotensin II (Ang II)

Antibody Type: Recombinant Antibody

Reactivity: Rat

Host: Rabbit

Clonality: Chimeric

Conjugate: This Angiotensin II antibody is un-conjugated

Application: Please inquire

Clone: KAA8

Product Details anti-Angiotensin II Antibody

Purpose: Anti-Angiotensin II [KAA8], Rabbit IgG, kappa

Cross-Reactivity: Human

Characteristics:

Original Species of Ab: Mouse

Original Format of Ab: IgG

Purification: Protein A affinity purified

Immunogen: Angiotensin II

Isotype: IgG kappa

Application Details

Application Notes: Angiotensin II is a potent regulator of blood pressure, body fluid and electrolyte homeostasis. It acts directly on vascular smooth muscle as a potent vasoconstrictor, affects cardiac contractility and heart rate through its action on the sympathetic nervous system, and alters renal sodium and water absorption through its ability to stimulate the zona glomerulosa cells of the adrenal cortex to synthesize and secrete aldosterone.

Comment:

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG format, for improved compatibility with existing reagents, assays and techniques.

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Target Details for Angiotensin II

Target: Angiotensin II (Ang II)

Alternative Name: Angiotensin II

Background: Octapeptide hormone angiotensin II, AII

UniProt: P01019

Pathways: JAK-STAT Signaling, ACE Inhibitor Pathway, EGFR Signaling Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Regulation of Lipid Metabolism by PPARalpha, Protein targeting to Nucleus, Feeding Behaviour, Regulation of long-term Neuronal Synaptic Plasticity