Recombinant Tyrosinase-Related Protein 1 antibody

Catalog No. ABIN7487762

This Human Chimeric antibody specifically detects Tyrosinase-Related Protein 1 in IF, FACS, WB, ELISA, IHC (fro) and IP. It exhibits reactivity toward Human.

Quick Overview for Recombinant Tyrosinase-Related Protein 1 antibody (ABIN7487762)

Target: Tyrosinase-Related Protein 1 (TYRP1)

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Human

Clonality: Chimeric

Conjugate: This Tyrosinase-Related Protein 1 antibody is un-conjugated

Application: Immunofluorescence (IF), Flow Cytometry (FACS), Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP)

Clone: TA99

Product Details anti-Tyrosinase-Related Protein 1 Antibody

Purpose: Anti-TRP-1, gp75 [TA99], Human IgG1, kappa

Specificity: Binds Tyrosinase-related protein-1 (TRP-1), a 70-75k enzyme located in melanocytes, which are specialized cells that produce a pigment called melanin, helping to stabilize tyrosinase, which is the enzyme responsible for the first step in melanin production and determine the shape of melanosomes, which are the structures in melanocytes where melanin is produced.

Characteristics:

Original Species of Ab: Mouse

Original Format of Ab: IgG2a

Purification: Protein A affinity purified

Immunogen: 70-75 kDa pigmentation-associated glycoprotein in human melanoma cell lines.

Isotype: IgG1 kappa

Application Details

Application Notes: This antibody binds to human and murine TRP-1 and had been under evaluation for the treatment of tumours.

Comment:

This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques.

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Target Details for Tyrosinase-Related Protein 1

Target: Tyrosinase-Related Protein 1 (TYRP1)

Alternative Name: TRP-1, gp75

Background: Melanoma antigen gp75, 5,6-dihydroxyindole-2-carboxylic acid oxidase, DHICA oxidase, Catalase B, Glycoprotein 75, Tyrosinase-related protein 1, TRP, TRP-1, TRP1

UniProt: P17643