FCRL4 antibody
Quick Overview for FCRL4 antibody (ABIN7505906)
Target
See all FCRL4 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Purpose
- Anti-Hu CD307d Purified
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Characteristics
- The mouse monoclonal antibody A1 recognizes an epitope within extracellular domain of CD307d, a transmembrane glycoprotein expressed mainly on memory B cells.
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Purification
- Purified by protein-A affinity chromatography.
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Immunogen
- DNA-immunization followed by a boost with CD307d-transfected cells
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Isotype
- IgG2a, kappa
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Application Notes
- Flow cytometry: Recommended dilution: 2-5 μg/mL.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Do not freeze
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Storage
- 4 °C
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Storage Comment
- Store at 2-8°C. Do not freeze.
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- FCRL4 (Fc Receptor-Like 4 (FCRL4))
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Alternative Name
- CD307d
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Background
- Fc receptor like 4,CD307d is a type I transmembrane glycoprotein of the Fc receptor family. It contains two ITIM motifs and one ITSM motif in its cytoplasmic domain. CD307d is expressed mainly on the surface of memory B cells in mucosa-associated lymphoid tissues. It binds to aggregated immunoglobulin molecules (IgA, IgG). Defects of CD307d may play a role in HIV-induced memory B cell dysfunction.,FcRL4, FCRH4, IRTA1
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Gene ID
- 83417
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UniProt
- Q96PJ5
Target
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