FCRL4 antibody (Fc Region)

Catalog No. ABIN7875221

This Rabbit Polyclonal antibody specifically detects FCRL4 in WB and FACS. It exhibits reactivity toward Human.

Quick Overview for FCRL4 antibody (Fc Region) (ABIN7875221)

Target: FCRL4 (Fc Receptor-Like 4 (FCRL4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FCRL4 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Product Details anti-FCRL4 Antibody

Binding Specificity: AA 480-507, Fc Region

Purpose: FCRL4 Antibody / Fc receptor-like protein 4

Purification: Antigen affinity

Immunogen: A portion of amino acids 480-507 from the human protein was used as the immunogen for the FCRL4 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the FCRL4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Aliquot the FCRL4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for FCRL4

Target: FCRL4 (Fc Receptor-Like 4 (FCRL4))

Alternative Name: FCRL4

Background: Fc receptor-like proteins (FCRLs) are a family of receptors that resemble Fc receptors, which are usually found on immune cells and are involved in recognizing and binding to antibodies. FCRL4, in particular, has been shown to be expressed on B cells and T cells, suggesting its involvement in immune regulation. One of the key functions of FCRL4 is its ability to modulate the activation and signaling pathways of immune cells. Studies have indicated that FCRL4 may play a role in regulating B cell responses, including antibody production and immune cell activation. Additionally, FCRL4 has been linked to autoimmune diseases, such as rheumatoid arthritis and systemic lupus erythematosus, highlighting its importance in immune dysregulation.

UniProt: Q96PJ5