Podoplanin antibody (Cancer Type)
Quick Overview for Podoplanin antibody (Cancer Type) (ABIN7506002)
Target
See all Podoplanin (PDPN) AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- Cancer Type
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Purpose
- Anti-Hu PDPN (cancer type) Purified
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Characteristics
- The mouse monoclonal antibody LpMab-23 recognizes an extracellular epitope on human cancer type PDPN, a transmembrane glycoprotein, serving as a prognostic marker of oral carcinoma. This antibody recognizes an altered glycosylation pattern that occurs on oral cancer cells and it shows minimal reactivity with the surrounding non-cancerous tissue.
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Purification
- Purified by protein-A affinity chromatography.
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Immunogen
- recombinant human PDPN
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Isotype
- IgG1, kappa
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Application Notes
- Flow cytometry: Recommended dilution: 1-5 μg/mL.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Do not freeze
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Storage
- 4 °C
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Storage Comment
- Store at 2-8°C. Do not freeze.
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- Podoplanin (PDPN)
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Alternative Name
- PDPN
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Background
- Podoplanin,PDPN (podoplanin) is a type I transmembrane glycoprotein of mucin-type character. The specific function of this protein has not been determined, but its homologs in other species were described as differentiation antigens. PDPN can be used as a marker of lung injury. Alternatively spliced transcript variants encoding different isoforms have been identified.,podoplanin, AGGRUS, OTS8, T1A2, T1A1
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Gene ID
- 10630
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UniProt
- Q86YL7
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Pathways
- Dicarboxylic Acid Transport
Target
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