SIGLEC10 antibody (Extracellular Domain)

Catalog No. ABIN7506009

This Mouse Monoclonal antibody specifically detects SIGLEC10 in IHC, ELISA and IP. It exhibits reactivity toward Human.

Quick Overview for SIGLEC10 antibody (Extracellular Domain) (ABIN7506009)

Target: SIGLEC10 (Sialic Acid Binding Ig-Like Lectin 10 (SIGLEC10))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SIGLEC10 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP)

Clone: 5G6

Product Details anti-SIGLEC10 Antibody

Binding Specificity: Extracellular Domain

Purpose: Anti-Hu SIGLEC10 Purified

Characteristics: The mouse monoclonal antibody 5G6 recognizes an extracellular epitope of human SIGLEC10, a sialic acid-binding lectin expressed on subsets of human leucocytes.

Purification: Purified by protein-A affinity chromatography.

Immunogen: SIGLEC10 extracellular domain fused with human IgG1 Fc fragment

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze

Storage: 4 °C

Storage Comment: Store at 2-8°C. Do not freeze.

Target Details for SIGLEC10

Target: SIGLEC10 (Sialic Acid Binding Ig-Like Lectin 10 (SIGLEC10))

Alternative Name: SIGLEC10

Background: Sialic acid binding Ig like lectin 10,SIGLEC10 is a CD33-related receptor of sialoglycans, expressed on eosinophils, monocytes, a subpopulation of NK cells, and at lower level on B cells. Its murine ortholog is Siglec G. SIGLEC10 seems to act as an immunomodulatory receptor, which binds to VAP-1, a glycoprotein expressed on endothelium under inflammatory conditions. Another ligand of SIGLEC10 is CD24, a marker of poorer prognosis in carcinomas.,PRO940, SGL2

Gene ID: 89790

UniProt: Q96LC7