Recombinant ErbB2/Her2 antibody (pTyr1248)

Catalog No. ABIN7516220

This Rabbit Monoclonal antibody specifically detects ErbB2/Her2 in WB and IP. It exhibits reactivity toward Human.

Quick Overview for Recombinant ErbB2/Her2 antibody (pTyr1248) (ABIN7516220)

Target: ErbB2/Her2 (Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This ErbB2/Her2 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Clone: R03-6A8

Product Details anti-ErbB2/Her2 Antibody

Binding Specificity: pTyr1248

Purpose: Rabbit recombinant monoclonal antibody raised against synthetic phosphopeptide corresponding to residues surrounding Tyr1248 of human ErbB 2.

Cross-Reactivity: Human

Immunogen: Original antibody is raised against a synthetic phosphopeptide corresponding to residues surrounding Tyr1248 of human ErbB 2

Isotype: IgG

Application Details

Application Notes: Immunoprecipitation (1:20),Western Blot (1:500-1:1,000),The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 50 mM Tris-Glycine, pH 7.4 (0.15 M NaCl, 40 % Glycerol, 0.01 % Sodium azide and 0.05 % BSA).

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for short term. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

Target Details for ErbB2/Her2

Target: ErbB2/Her2 (Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2))

Alternative Name: ERBB2

Background: V-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)

Gene ID: 2064

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Skeletal Muscle Fiber Development