IFNA antibody (AA 101-189)

Catalog No. ABIN721810

This Rabbit Polyclonal antibody specifically detects IFNA in WB, ELISA, IHC (fro), IF (cc), IF (p) and IHC (p). It exhibits reactivity toward Human.

Quick Overview for IFNA antibody (AA 101-189) (ABIN721810)

Target: IFNA (Interferon alpha (IFNA))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IFNA antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-IFNA Antibody

Binding Specificity: AA 101-189

Specificity: This antibody will detect all 13 subtypes of Human IFN-Alpha

Predicted Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human IFNA1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for IFNA

Target: IFNA (Interferon alpha (IFNA))

Alternative Name: IFN-Alpha

Background:

Synonyms: IFNA, IFN-a, IFN-_, Interferon alpha, Interferon-alpha, IFNA1, IFNA13, IFNA1/13, IFNA4: IFNA5, IFNA6, IFNA17, IFNA21, IFNA8, IFNA2, IFNA7, IFNA14, IFNA10, IFNA16, Pan Interferon alpha

Background: Interferon-_ (IFN-_, also known as IFN-alpha, IFN-a, IFNA and Interferon-alpha) is a type I interferon and exists as 13 subtypes: IFN-_ 1, 2, 4, 5, 6, 7, 8, 10, 13, 14, 16, 17 and 21. They are mainly produced by virus-infected cells after sensing the presence of danger signals such as viral DNA or RNA. The binding of IFN-_ to its receptor initiates an anti-viral response, but also anti-tumor effects have been shown. A key producer of type I interferons is the plasmacytoid dendritic cell.

Gene ID: 3439

UniProt: P01562

Pathways: JAK-STAT Signaling, TLR Signaling, Hepatitis C, Inflammasome